Current Literature

The impact of root canal treatment on the quality of life was apparent. Satisfaction with RCT approximates 8 on the differential scale. Preference for specialists over dental students.

The furcal aspect of the entire mesial root should be considered a “danger zone.” Mesial canals were found to be much more variable than distal canals in morphology, though orifice location remains relatively consistent. Root-end resection of 3 mm would remove the majority of lateral canals and apical ramifications.

Available evidence suggests that apical periodontitis (AP) is associated with increased levels of some systemic inflammatory mediators in humans. Untreated AP may have a pro-atherogenic effect with a potential role in patient’s global vascular risk. Suggests AP may contribute to systemic inflammation, and not be localized to the lesion

Root canal procedures can potentially initiate and propagate cracks from within the root canal in the apical region

Lesion changes after root canal treatments determined with 3D volumetric CBCT data and 2-dimensional PA data were different, and outcome determined with PA could be untrue (This statement is not supported by author’s result).

Tissue formed in the canal during revascularization was well-mineralized cementum- or bone-like tissue

The results of this study indicate that when either of these materials is used for perforation repairs, pulp capping, or as an apical barrier, wait at least 36 hours for MTA to set and even longer to allow ESRRM to set before continuing either endodontic or restorative procedures.

The minimum diameter of the apical foramen to allow ingrowth is not determined, but a diameter much smaller than 1 mm does not prevent revascularization and ingrowth of new vital tissue (histologically).

Data from the study suggests that polymorphisms in the CD14 and TLR4 genes do not influence the response to endodontic treatment of teeth with apical periodontitis.

The results of this study have showed that the pattern for further
root maturation of roots after regenerative procedures was variable when assessed at 18 months, although in almost all cases, periapical pathology appeared to resolve completely.