Creative Podcaster

Oral Medicine and drug interactions​

Adverse drug interactions in dental practice: interactions associated with analgesics, Part III in a series

Purpose:   overview of drug interactions with analgesics and identifies those that are clinically relevant. Most highlighted Results:  NSAIDs and antihypertensives. •There is sufficient evidence to support an interaction between NSAIDs and three major classes of antihypertensives: 1.Angiotensin-converting enzyme inhibitors, or ACEIs, such as captopril 2.Diuretics such as furosemide 3.ß-blockers such as propranolol NSAIDs may attenuate …

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The changing spectrum of Clostridium difficile–associated disease Implications for dentistry

Case 1 (mild CDAD ): A 48-year-old female received antibiotics (oral clindamycin) after undergoing endodontic surgery.  8 days after the antibiotic course, she had diarrhea, she took metronidazole, and her C. difficile infection resolved. Case 2 (severe CDAD): A 31-year-old pregnant woman developed severe CDAD after receiving antibiotics for a urinary infection. She underwent surgery …

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Dental treatment planning and management in the patient who has cancer

Summary:  •The following are the goals of dental management before the start of cancer therapy: Eliminate or stabilize oral disease to minimize local and systemic infection during and after cancer therapy: •Short term:  Ideally, all patients should be returned to a stable, if not perfect state of dental health before cytoreductive therapy •long term:  the …

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Interference of cardiac pacemaker and implantable cardioverter-defibrillator activity during electronic dental device use

Summary:   •Purpose: to determine if electromagnetic interference of cardiac pacemaker and implantable cardioverter-defibrillator (ICD) activity occurs during the operation of electronic dental devices.  Materials/Methods: Pacemakers and implantable cardioverter-defibrillators (ICDs) are electronic devices that emit electrical signals and are sensitive to electromagnetic signals in the vicinity. Nine electronic dental devices in vitro to assess their …

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The immuno cross-reactivity of gutta percha points.

•Purpose: To examine the potential cross-reactivity between raw gutta percha, raw gutta balata, gutta percha points and NRL proteins by the inhibition enzyme linked immunosorbent (ELISA) and the FITkit assays. • Materials/Methods: Different brands of gutta percha points, raw gutta balata and NRL gloves were obtained Samples were cut into 1–2 mm pieces. One gram …

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Pregnancy: Physiologic Changes and Considerations for Dental Patients

Summary:  •Pregnancy is a dynamic physiological state evidenced by several transient changes. •The most common complaints include nausea and vomiting, nasal congestion, heartburn, alteration in taste and food cravings, hyperventilation, shortness of breath, and fatigue. •Physiologic changes during pregnancy: Increase oxygen demand. The liver has increased hepatic production of hormone-binding globulins and decreased albumin, resulting …

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European Society of Endodontology position statement: the use of antibiotics in endodontics. 

Purpose: is to provide dentists and other healthcare workers with evidence-based criteria for when to use antibiotics in the treatment of endodontic infections, traumatic injuries of the teeth, revascularization procedures in immature teeth with pulp necrosis, and in prophylaxis for medically compromised patients . •Most endodontic infections are confined within the tooth and can be …

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Impact of diabetes mellitus, hypertension, and coronary artery disease on tooth extraction after nonsurgical endodontic treatment.

Purpose: to assess the impact of systemic diseases (diabetes (DM), hypertension (HT) and coronary artery disease (CAD)) on the risk of tooth extraction after NSRCT. N= 49,334 teeth treated with NSRCT. Excluded: Those with missing data or coding errors, deciduous teeth, and multiple teeth from 1 patient. Materials/Methods: •A total of 49,334 NSRCT teeth were …

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