Comparison of Radicular Peroxide Leakage from four Commonly used Bleaching agents following Intracoronal Bleaching in Endodontically treated teeth – An In Vitro Study

By Madhu KS, Hegde S, Mathew S, Lata DA, Bhandi SH, Shruthi N

Date: 01/2013
Journal: JIOH


To compare the amount of peroxide leakage of four different bleaching agents


N= 50 extracted maxillary centrals

Teeth accessed and treated; obturation with gutta percha and AH + , Access sealed with Cavit, and outer root surface coted with wax and nail varnish, and roots incubated 7 days in distilled water. 3 mm of Gutta percha removed and glass ionomer cement placed. Bleaching agent was placed in the pulp chamber:

  • Group 1- distilled water
  • Group 2- Sodium perborate with distilled water
  • Group 3- 30 % Hydrogen Peroxide
  • Group 4- Sodium perborate and 30 % hydrogen peroxide
  • Group 5- 10 % carbamide peroxide gel

Peroxide leakage measured using spectrophotometer, ANOVA statistical analysis, Bonferroni comparisons


  • Peroxide Penetration significantly different: Group 3 > Group 4 > Group 2 > Group 5

Clinical Significance:

Peroxide leakage is least in carbamide peroxide compared to other groups and may be a safer alternative to the other methods tested.