This study was designed to evaluate histologically the pulpal response to the application of heat and hydrogen peroxide, separately and together, to young human teeth.
- N= 28 premolars free of caries and restorations scheduled for orthodontic extractions. No tetracycline stains present
- n=7 teeth for each group
Group 1. Control group, which was not treated.
Group 2. Teeth treated with heat and a 35% hydrogen peroxide solution (Superoxol) for five-minute intervals, in two appointments, spaced four days apart.
Group 3. Same as Group 2, except physiologic saline solution was substituted for the hydrogen peroxide.
Group 4. Teeth treated with hydrogen peroxide solution, without heat application, for five-minute intervals, in two appointments, spaced four days apart.
Four days after the second appt. Extractions, fixed and stained for histologic examination.
- Application of heat ranging from 115 to 124 F and a 35% solution of hydrogen peroxide to intact human premolars causes a mild superficial inflammation (graded 0.5 to 1.0) in a significant number of pulps.
- Peroxide alone, or heat with saline solution, was judged to be less irritating since it did not cause a significant number of inflammatory responses.
Heat and hydrogen peroxide cause mild pulpal inflammation.