Purpose: to determine the effect of dilution on the ability of NaOCl to dissolve necrotic tissue. Compare tissue dissolution properties of NaOCl, normal saline, distilled water, 3% H2O2.
N= 63 specimens (from rat)
- Tissue specimen 13 mm diameter (epithelium and connective tissue; the muscle and fat layers), placed in distilled water for 7 min, placed on filter paper, Specimens were weighted .
- Test solution was added (1 ml of solution /10 mg of tissue). Stirred for 7 min automatically. percent of weight loss or gain=(weight of the filter paper+ mean residual moisture)/(original tissue weight)
- Test solution were 5.25, 2.5, 1, 0. 5% NaOCl, normal saline, 3% H2O2.
Most highlighted Results:
- Mean weight change (table1).
- 5.25% NaOCI was significantly more effective as a necrotic tissue solvent than any of the other test solutions
As the concentration of NaOCl increases it becomes more effective.