Does Low-Dose Aspirin Therapy Complicate Oral Surgery Procedures?

By Ardekian L, Gaspar R, Peled M, Brener B, Laufer D.

Date: 01/2000
Journal: JADA


The aim of the present study is to evaluate the effect of low-dose aspirin on bleeding in patients undergoing oral surgery.


  • N=39 patients were receiving 100 milligrams of aspirin daily on a regular basis, who were scheduled for dental extractions.
  • Divided randomly into two groups: (Control)20 who stopped the aspirin therapy 7 days before the procedure and (experimental) 19 who continued the aspirin therapy.
  • One hour before the procedures, all patients underwent a bleeding time test. In addition, the amount of bleeding during the procedure was measured by subtracting the amount of irrigant from the volume of collected suction.


  • The mean bleeding time was 1.8 +/-0.47minutes for control group and 3.1+/-0.65 minutes for experimental group. Statistically significant.
  • Local hemostatic method was sufficient to control bleeding in both groups.

Clinical Significance:

Low-dose aspirin therapy should not be stopped before oral surgery. Local hemostasis is sufficient to control bleeding.