Hemostatic Efficacy and Cardiovascular Effects of Agents Used During Endodontic Surgery

By Vickers F J , Baumgartner JC , Marshall G

Date: 12/2002
Journal: JOE

Summary:  

Purpose: To evaluate ferric sulfate and epinephrine-impregnated cotton pellets and  their ability to achieve hemostasis during endodontic surgical procedures and for cardiovascular changes

Materials/Methods: 

•33 patients participated in this study

•The patients were randomly assigned to one of two groups.

In group I, hemostasis was achieved by using 20% ferric sulfate.

In group 2, hemostasis was achieved by using racemic-epinephrine cotton pellets.

•Blood pressure was recorded preoperatively , immediately after surgery and before patients dismissal

A Most highlighted Results: 

  1.There were no significant changes in blood pressure or pulse at any time period for experimental groups 1 and 2

2.. In group 1 (ferric sulfate), adequate hemostasis was achieved in 15 out of 16 cases, with one case having inadequate hemostasis.

3.In group 2 (epinephrine pellets), adequate hemostasis was achieved in all 17 cases.

4.Racellet #3 pellets contain an average of 0.55 mg (0.42 to 0.68 mg/pellet) of racemic-epinephrine hydrochloride per pellet,

Clinical significance: 

.  Using the racemic epinephrine pellets showed good  hemostasis in endodontic surgery .