Purpose:
- To evaluate healing responses following repair of furcation perforations, with and without an internal matrix and to evaluate the efficacy of 2 matrix materials
Materials/Methods:
- N= 80 teeth (2 Premolars + 3 molars per quadrant in 4 baboons)
- Internal matrix materials: HAPSET (65 % non-resorbable hydroxyapatite, 35 % plaster of paris) and hydroxyapatite (HA). If repaired, amalgam was the repair material.
- Following furcation perforations (rubber dam isolation), teeth randomly assigned into 5 groups : HAPSET + Amalgam , HA + Amalgam, no matrix + Amalgam, Positive control- no repair, and Negative control- No perforation
- Animals sacrificed for histologic examination at 1 week and 1, 3, and 7 months
Results:
- Positive controls and no matrix + amalgam groups showed severe inflammation for the duration of the study
- Using a matrix prevents extrusion of the amalgam thus decreasing severity and duration of the inflammatory response
- There is no difference in tissue response to HAPSET and HA. Both materials underwent initial connective tissue encapsulation followed by directly contacting bone deposition (no intervening connective tissue)
Clinical Significance:
When performing non-surgical furcation perforation repair, use of an internal matrix material will limit repair material extrusion, which reduces long-term inflammation. No difference between HAPSET and HA in terms of duration of inflammation and both promoted bone deposition directly contacting the repair material