Evaluation of healing with use of an internal matrix to repair furcation perforations

By Rafter M, Baker M, Alves M, Daniel J, Remeikis N.

Date: 01/2002
Journal: IEJ

Purpose:

  • To evaluate healing responses following repair of furcation perforations, with and without an internal matrix and to evaluate the efficacy of 2 matrix materials

Materials/Methods:

  • N= 80 teeth (2 Premolars + 3 molars per quadrant in 4 baboons)
  • Internal matrix materials: HAPSET (65 % non-resorbable hydroxyapatite, 35 % plaster of paris) and hydroxyapatite (HA). If repaired, amalgam was the repair material.
  • Following furcation perforations (rubber dam isolation), teeth randomly assigned into 5 groups : HAPSET + Amalgam , HA + Amalgam, no matrix + Amalgam, Positive control- no repair, and Negative control- No perforation
  • Animals sacrificed for histologic examination at 1 week and 1, 3, and 7 months

Results:

  1. Positive controls and no matrix + amalgam groups showed severe inflammation for the duration of the study
  2. Using a matrix prevents extrusion of the amalgam thus decreasing severity and duration of the inflammatory response
  3. There is no difference in tissue response to HAPSET and HA. Both materials underwent initial connective tissue encapsulation followed by directly contacting bone deposition (no intervening connective tissue)

Clinical Significance:

When performing non-surgical furcation perforation repair, use of an internal matrix material will limit repair material extrusion, which reduces long-term inflammation. No difference between HAPSET and HA in terms of duration of inflammation and both promoted bone deposition directly contacting the repair material