Ferric Sulfate Hemostasis: Effect on Osseous Wound Healing—II: with Curettage and Irrigation.

By Jeansonne BG, Boggs WS, Lemon RR.

Date: 01/1993
Journal: JOE

Purpose:

To evaluate the effectiveness of ferric sulfate as a hemostatic agent and to determine its effect on healing after thorough curettage and irrigation from osseous surgical wounds.

Materials/Methods:

  • N= 12 rabbits
  • Ferric sulfate was placed in one defect until hemostasis was obtained; the contralateral defect was allowed to fill with blood and clot. After 5 minutes, both defects were curetted and irrigated. Evaluated histologically at 18 and 46 days.

Results:

When ferric sulfate is adequately curetted and irrigated from the surgical site prior to closure, persistent inflammation or delay in osseous repair was less compared to controls.

Clinical Significance:

Ferric Sulfate may be a good hemostatic agent during retrograde RCT.