Hemostatic Efficacy and Cardiovascular Effects of Agents Used During Endodontic Surgery

By Vickers F.J., Baumgartner J.C., Marshall G.

Date: 01/2002
Journal: JOE

Purpose:

The hemostatic efficacy, as well as the cardiovascular effects of racemic-epinephrine pellets (Racellet pellets) vs. 20% ferric sulfate (Viscostat).

Materials/Methods:

  • N=39 for periapical surgery, Inclusion: ASA class I & II. Group 1=ferric sulfate Group 2= racellet pellets.
  • Blood pressure and pulse rate were recorded pre- and postoperatively and at at 1, 5, and 10 min after placement.
  • The adequacy of hemostasis was rated by the surgical operator.

Results:

  1. Surgical hemostasis achieved in 15 out of the 16 treated with Ferric Sulfate and all 17 cases treated with racemic-epinephrine pellets.
  2. No significant change in cardiovascular effects when using either of these hemostatic agents.

Clinical Significance:

Racemic-epinephrine (Epinephrine concentration # 2 = 0.55 mg/pellet) pellets can be used for hemostasis with no cardiovascular effect.