Comparison of the antimicrobial efficacy of 1.3% NaOCl/BioPure MTAD to 5.25% NaOCl/15% EDTA for root canal

By Johal S, Baumgartner JC, Marshall JG.

Date: 10/2007
Journal: JOE

Summary:

  •Purpose: To compare the antimicrobial efficacy of 1.3% NaOCl/BioPure MTAD to 5.25% NaOCl/15% EDTA for root canal irrigation.

•N= 26 bilaterally matched pairs of human teeth

Materials/Methods:

•Teeth were incubated with Enterococcus faecalis for 4 weeks.

•The teeth were divided into two experimental groups and one positive control group.

•The canals were instrumented and irrigated with either 5.25% NaOCl/15% EDTA or 1.3% NaOCl/BioPure MTAD.

•Bacterial samples were collected after instrumentation/irrigation and after additional canal enlargement.

Most highlighted Results:

•Significant differences between the experimental groups.

•None of the samples revealed growth in 5.25% NaOCl/15% EDTA irrigation group in the first bacterial samples.

•8 of 20 samples with 1.3% NaOCl/BioPure MTAD irrigation revealed growth in the first bacterial samples.

•None of the samples revealed growth in 5.25% NaOCl/15% EDTA irrigation group after additional canal enlargement.

•10 of 20 samples in 1.3% NaOCl/BioPure MTAD group revealed growth after additional canal enlargement.

Clinical significance:

The combination of 1.3% NaOCl/BioPure MTAD left nearly 50% of the canals contaminated with E. faecalis.