Summary:
•Purpose: To compare the antimicrobial efficacy of 1.3% NaOCl/BioPure MTAD to 5.25% NaOCl/15% EDTA for root canal irrigation.
•N= 26 bilaterally matched pairs of human teeth
•Materials/Methods:
•Teeth were incubated with Enterococcus faecalis for 4 weeks.
•The teeth were divided into two experimental groups and one positive control group.
•The canals were instrumented and irrigated with either 5.25% NaOCl/15% EDTA or 1.3% NaOCl/BioPure MTAD.
•Bacterial samples were collected after instrumentation/irrigation and after additional canal enlargement.
•Most highlighted Results:
•Significant differences between the experimental groups.
•None of the samples revealed growth in 5.25% NaOCl/15% EDTA irrigation group in the first bacterial samples.
•8 of 20 samples with 1.3% NaOCl/BioPure MTAD irrigation revealed growth in the first bacterial samples.
•None of the samples revealed growth in 5.25% NaOCl/15% EDTA irrigation group after additional canal enlargement.
•10 of 20 samples in 1.3% NaOCl/BioPure MTAD group revealed growth after additional canal enlargement.
Clinical significance:
The combination of 1.3% NaOCl/BioPure MTAD left nearly 50% of the canals contaminated with E. faecalis.
