Purpose: To assess the effects of irrigants used in the non-surgical root canal treatment of mature permanent teeth.
Search was conducted using Chochrane, MEDLINE, EMBASE, and LILACS up to 5th of July 2012
Inclusion & Exclusion:
– n: 11 trials involving 851 participants with 879 teeth
– 4 studies (Bashetty 2010; Ercan2004;Ringel 1982;Vianna 2006) concluded that there were No significant difference between NaOCL and CHX in reducing the bacterial growth with different conc. and form (gel or solution)
-1 study (Soares 2006) concluded that there were a difference between 1% NaOCL concertation and 5% NaOCL in the number of positive cultures (but not significant)
-1 study (Harrison 1978) concluded that there were no evidence supporting the effect of different irrigation solutions (saline, 5.25% NaOCL, 5.25% NaOCL with 3% Hydrogen peroxide) to interappointment pain.
-1 study (Tachieri 2009) concluded that there were no notable difference between 5% NaOCL and 5% NaOCL with proteolytic enzyme in post-operative pain and cases with new or worsening S&S.
-Zamany 2003 reported no sig difference in bacterial growth following final irrigation with either 2% CHX or saline after initial irrigation with 1% NaOCL.
– Malkhassian 2009 reported reduced bacteria when 1.3% NaOCL used with MTAD than when saline used alone
-Bebeck 2009 reported difference of bacterial growth between 2% CHX and saline
-Torbinejad 2005 reported average pain at day 7 in both irrigation regime (Sodium hypochlorite 5.25% with EDTA (17%) versus sodium hypochlorite 1.3% with MTAD)
There was insufficient clear evidence to support the outright superiority of any specific individual irrigant or irrigating regime.