Healing of apical periodontitis after endodontic treatment with and without obturation in dogs​

By Sabeti MA, Nekofar M, Motahhary P, Ghandi M, Simon JH

Date: 11/2006
Journal: JOE

Summary:  ​

Purpose:  to investigate the importance of obturation in healing of periapical periodontitis.​

N=  56 root canals in 28 3rd and 4th bilateral lower premolar teeth with completely formed apices in 7 dogs. ​


  • PA lesions were induced in all the teeth by pulp extirpation and leaving the canals open to the oral environment. ​
  • The teeth were divided into 2 groups: control and experiment group.​
  • teeth in the control group were accessed, instrumented irrigated and oburated by cold lateral compaction.​
  • teeth in the experiment group were accessed, instrumented irrigated but not obturated.​
  • In both groups, the teeth were sealed coronally.​
  • after 6 months, animals were killed, 5-m thick sections were obtained from each root and stained with for histological​


Most highlighted Results:  ​

  • The control group (with obturation) showed less cementum and dentin resorption in comparison with test group (no obturation) (P<0.05)​
  • No statistically significant difference was found in other parameters between the control and test groups (table 1).​
  • No difference in healing of apical periodontitis between the 2 groups​

Clinical significance:  

obturation is not significant for endodontic treatment success. ​