•Purpose: to compare the outcome of root canal obturation by warm GP with that by CLC
•N= 10 articles met inclusion criteria
•Randomized controlled trials and controlled clinical trials comparing obturation by warm GP versus CLC conducted in humans were identified. •Inclusion criteria:
(a) teeth with irreversible pulp disease or chronic apical periodontitis;
(b) not received any RCT;
(c) outcome was evaluated by clinical symptoms /radiographic evidence.
(a) studies were not RCTs or preliminary quasi-RCTs;
(b) studies were carried out in vitro or on retreatment cases;
(c) studies with no comparison between warm GP and CLC filling techniques;
(d) no healing rate was presented;
(e) full text could not be located.
•All searches were conducted independently by at least two reviewers.
•Meta-analysis data summary for outcomes of root canal obturation using warm GP versus CLC in terms of postoperative pain prevalence, long-term outcome, obturation quality, and rate of overextension.
•Most highlighted Results:
1.The prevalence of overextension in the warm GP group was significantly higher than that in the CLC.
2.The obturation quality, long-term outcome, and postoperative pain prevalence did not show statistical differences and were similar between these two groups. Table 2
A greater incidence of overextension is seen in the warm GP obturation than in the CLC.