Periapical Inflammation after Coronal Microbial Inoculation of Dog Roots Filled with Gutta-Percha or Resilon ​

By Shipper G, Teixeira F, Arnold R, Trope M

Date: 06/2006
Journal: JOE


Purpose: compare in vivo the efficacy of gutta-percha and AH26 sealer versus RMS filled roots in preventing apical periodontitis subsequent to coronal inoculation with oral microorganisms. ​

N= 133 dog’s premolar ​


  • pre-operative RG was taken ​
  • 56 vital teeth were accessed under sterile conditions. Instrumented to #40 k-file, profile rotary. G1: filled with lateral condensation with gutta percha and AH 26, G2: vertical gutta percha and AH 26. G3: lateral condensation resilon and Epiphany. G4: vertical condensation resilon and Epiphany.  All experimental groups closed with cotton and GIC.​
  • Negative control: filled with resilon or gutta percha and closed with cavit and GIC. Positive control: accessed inoculated with plaque closed with GIC. Experimental groups (1-4) were inoculated with plaque after 14 weeks. Then after 14 weeks of inoculation dog jaws were prepared for histological evaluation. ​
  • All teeth, were examined each month to verify the integrity of the restorations. ​

Most highlighted Results:  

-Mild inflammation was significantly more in gutta percha (82%) than resilon (20%).​

-All positive control showed on RG, PA lesion by the 6th week. (no histology done for this group),none of the experimental groups showed signs of apical periodontitis on RG.​

-No difference was found between negative control and resilon group.​​

Clinical significance: 

  •  This study showed that resilon is resistant to microleakage  ​