Purpose: to investigate the influence of an unfilled space and other local factors normally associated with endodontic repair on the healing of connective tissue.
N= 24 implants implanted in 6 rats.
- Varying lengths (4, 6, 10 mm) and diameters (0.58- 0.1.4mm) of polyethylene tubing were surgically implanted into the dorsal subcutaneous tissues of rats.
- half of the tubes were open at both ends, the other half had one end sealed. The tubes were left implanted for a period of 60 days, following which the animals were killed and the implants, together with the surrounding tissue, were excised.
- Specimens were then fixed in 10% formalin and sectioned serially and stained with hematosylin and eosin stain
Most highlighted Results:
- After 60 days the tubes were surrounded by a non-inflamed connective tissue capsule.
- in the open tubes: ingrowth of connective tissue occurred throughout the length of tubes of shorter lengths and larger diameters.
- In the closed tubes, the ingrowth was observed in the upper 0.25 to 0.5 mm. this invagination occurred primarily in tubes of the smaller diameters.
The over-all findings of the study indicated that under-filling a root canal which has been thoroughly and completely cleaned and adequately disinfected would probably result in healing of the surrounding peri-apical tissue.