Purpose: to assess the impact of systemic diseases (diabetes (DM), hypertension (HT) and coronary artery disease (CAD)) on the risk of tooth extraction after NSRCT.
- N= 49,334 teeth treated with NSRCT. Excluded: Those with missing data or coding errors, deciduous teeth, and multiple teeth from 1 patient.
•A total of 49,334 NSRCT teeth were randomly selected from databank in October 2003 and were followed for 2 years for tooth extraction after NSRCT.
•DM was defined as having a fasting plasma glucose level ≥126 mg/ dL on 2 or more tests on different days, a random blood glucose level ≥ 200 mg/dL, hemoglobin A1c >6.5% , or a history of treated DM.
•HT was defined as having repeated elevated blood pressure with systolic blood pressure ≥140 mm Hg and diastolic blood pressure ≥ 90 mm Hg, or history of treated HT.
Most highlighted Results:
- Of the 49,334 teeth, 1592 (3.2%) were extracted during the 2-year follow-up period, yielding a 2-year tooth retention rate of 96.8%.
- DM, HT, and CAD were significant risk factors for tooth extraction after NSRCT (all P values <.0001) (Hazard ratio HR: >1.7)
- After adjustment for age, gender, and tooth type in multivariate analyses, DM (HR, 1.29) and HT (HR, 1.18) remained as independent significant risk factors (P values <.05).
- Having 2 diseases of DM, HT, and CAD was a significant and robust predictor for an increased long-term risk of tooth extraction after NSRCT (P<0.001). HR=1.53