Perforation repair comparing two types of mineral trioxide aggregate

By Ferris DM, Baumgartner JC.

Date: 01/2005
Journal: JOE

Purpose:   to compare the ability of two types of MTA (Gray & off-white) for sealing furcation perforations in extracted human molars using an anaerobic, bacterial-leakage model.

N=  40 extracted mandibular and maxillary molars.

•Difference between gray and off-white MTA:  the off-white-colored formula lacks the tetracalcium aluminoferrite. The lack of this iron-containing compound may account for its off-white appearance.

•Both types are 75% Portland cement, 20% bismuth oxide, and 5% gypsum by weight



a) Experimental group 1 (n=18): Perforation repaired with gray-colored MTA

b)Experimental group 2 (n=18) Perforation repaired with off-white-colored MTA.

c)Positive control (n=2) Perforation made but not repaired

d)Negative control (n=2) No perforations

•Standardized access cavities were prepared, and all the teeth surfaced were coated with 2 layers of nail polish.

•A high-speed bur was used to prepare furcal perforations.

•Teeth were randomly divided into the experimental groups based on the repair material.

•After perforation repair, A dual chamber anaerobic bacterial leakage model was assembled.

•Upper chamber contained the culture broth with Fusobacterium nucleatum, lower chamber contained sterile bacterial broth.

•The samples were observed every 2 to 3 days for turbidity of the broth, indicating bacterial growth from penetration of bacteria past the perforation repair.

•The experimental period last for 60 days.

Most highlighted Results:

•Between 15 and 21 days:

•(11%) gray-colored MTA samples leaked and

•(16%) off-white-colored MTA samples leaked

•There was no significant difference between the two types of MTA in preventing leakage of F. nucleatum  past furcal perforation repairs.

Conclusion: White MTA performed similarly to gray MTA in perforation repair.