Treatment Outcome of Repaired Root Perforation: A Systematic Review and Meta-analysis

By Siew K, Lee AH, Cheung GS

Date: 01/2017
Journal: JOE

Purpose: to review systematically the reported treatment outcome of repaired root perforation and to identify any preoperative factors that may influence the outcome of such repair.

Materials and methods:

•A search was conducted by using electronic databases as well as manual search of studies related to root perforation.

•The search covered all articles published from 1950 to July 2014. •Inclusion criteria:

1) Follow up more than one year. 

2) Permanent tooth.

3) Radiographs available.

4) Published in English or Chinese

Exclusion criteria:

1) Follow up less than one year.

2) Animal studies.

3) No outcome of treatment.

4)  Patient receiving long-term medication

•12 studies included and was screened by two reviewers independently.

Most highlighted results:

•An overall pooled success rate of 72.5% was estimated for nonsurgical repair of root perforations.

•The use of MTA appeared to enhance the success rate to 80.9% but was not statistically significant.

•The presence of pre-existing radiolucency adjacent to the perforation site had lower chance of success.

•Maxillary teeth demonstrated significantly higher success rate compared to mandibular teeth.

Clinical significance:

Non-surgical repair using MTA is considered as a promising treatment modality in root perforations.