Purpose: To investigate the role of infection on the prognosis of endodontic therapy by following-up teeth that had their RCT in a single appointment
N= 55 single rooted teeth
Inclusion: teeth with necrotic pulp and periapical lesion
•Access, initial sample, instrumentation up to #40, irrigation 0.5% NaOCl, post instrumentation sample, obturation with GP by lateral compaction & chloroform dipping technique.
•The cases were followed up yearly for 5 years.
•3 of the failure cases were analyzed histologically or by immunohistochemistry
Most highlighted Results:
•All initial samples yielded +Ve cultures •After instrumentation (40%) were positive and (60%) were negative to culture
•Complete periapical healing occurred in 94% of negative culture at the time of obturation and in 68% of the positive culture group (P<0.05) •Investigation of 3 failures revealed the presence of Actinomyces species in each case
•The size of PA lesion had no influence on tx. Outcome
The importance of thorough eliminating bacteria from the root canal system before obturation