Summary:
Purpose: To investigate the role of infection on the prognosis of endodontic therapy by following-up teeth that had their RCT in a single appointment
N= 55 single rooted teeth
Inclusion: teeth with necrotic pulp and periapical lesion
Materials/Methods:
•Access, initial sample, instrumentation up to #40, irrigation 0.5% NaOCl, post instrumentation sample, obturation with GP by lateral compaction & chloroform dipping technique.
•The cases were followed up yearly for 5 years.
•3 of the failure cases were analyzed histologically or by immunohistochemistry
Most highlighted Results:
•All initial samples yielded +Ve cultures •After instrumentation (40%) were positive and (60%) were negative to culture
•Complete periapical healing occurred in 94% of negative culture at the time of obturation and in 68% of the positive culture group (P<0.05) •Investigation of 3 failures revealed the presence of Actinomyces species in each case
•The size of PA lesion had no influence on tx. Outcome
Clinical significance:
The importance of thorough eliminating bacteria from the root canal system before obturation